In the meantime, high CI was related to high grade glioma (Figure 5B,C), IDH wildtype glioma (Figure 5D), 1p19q non-codeletion glioma (Figure 5E), MGMT unmethylated glioma (Figure 5F) and aggressive subtype glioma (Figure 5G). The gene discussed is MGMT; the disease is central nervous system cancer.