B3GNT8 and colorectal carcinoma: Regarding beta 3-glycosyltransferases, the role of β3GnT8 (UDP-GlcNAc:betaGalbeta-1,3-N-acetylglucosaminyltransferase 8) in CRC cell metastasis could be explained by decorating CD147 with β1,6-branched polylactosamine structures [22,27,33].