Molecules such as annexin A1, mucins, heat shock protein 90, β1 integrin, selectin ligands, carcinoembryonic antigen (CEA), epidermal growth factor receptor (EGFR), insulin-like growth factor-binding protein 3 (IGFBP3), transforming growth factor beta (TGF-β) receptors, Fas (CD95), PD-L1, sorbin and SH3 domain-containing protein 1 (SORBS1), decorin, CD147 and glycosphingolipids show variations in their glycosylation pattern in CRC tissues when they are compared with healthy tissues. Here, IGFBP3 is linked to colorectal carcinoma.