MECP2 and thyroiditis: It was also found that treatment with anti-thyroid agents, during neuronal development, causes a decrease in the number of parvalbumin-expressing GABAergic interneurons in the mouse cortex and hippocampus [216], as well as a decrease of the total thickness of the somatosensory, auditory, and visual cortices, with a decrease of the methyl-CpG binding protein 2 (MeCP2)-positive neuronal nuclei in the cortical layers II-IV [217].