STAT3 and stroke disorder: The same research group reported that M2 Mi-Exos also reduce glial scar formation and improve post-stroke recovery via miR-124, which inhibits the migration and proliferation of astrocytes by reducing the expression of signal transducer and activator of transcription 3 (STAT3), a direct target of miR-124, and phosphorylated-STAT3, the activated form of STAT3.