GPR17 and stroke disorder: In a recent study, Raffaele et al. stated that the infusion of pro-regenerative Mi-Exos in the peri-infarct area restores protective microglia/macrophage functions, preventing their senescence at later stages of stroke, and enhances the maturation of G protein-coupled receptor 17 (GPR17)-expressing oligodendrocyte precursor cells (OPCs), thereby increasing functional recovery.