TP53 and breast carcinoma: Additional breast CPGs implicated in moderate to severe breast cancer risk include BRCA1 Associated Ring Domain 1 (BARD1) [6], Tumor Protein P53 (TP53) [7], BRCA1 Interacting Protein 1 (BRIP1) [7], and RAD51 Paralog C (RAD51C) [8].