On the other hand, Kim et al., demonstrated no statistical significance for ultrasonographic high-suspicion features in BRAF V600E mutation-positive vs BRAF V600E (–) FVPTC patients, although FVPTC BRAF V600E (–) patients showed more frequent encapsulation and halo signs than BRAF V600E (+)patients [30]. The gene discussed is BRAF; the disease is follicular variant thyroid gland papillary carcinoma.