For instance, TRPC1 is involved in various tumor pathologies in a cancer stage-specific manner; inhibition of the expression or activity of TRPC1 mitigates cell adhesion and invasion ability in nasopharyngeal carcinoma [73], inhibits the migration of HCT-116 colon cancer cells and the proliferation of MDA-MB-468 breast cancer cell lines and leads to G(0)/G(1) cell cycle arrest of glioma and lung carcinoma cell lines [74]. Here, TRPC1 is linked to malignant colon neoplasm.