IL4 and rheumatoid arthritis: Our study revealed that the polymorphic variant of the IL4 [rs2243250] (T allele) is associated with the initial value of the disease activity according to DAS28 (p = 0.015), with the initial value of the clinical CDAI index (p = 0.014) and the risk of developing RA: OR = 1.6 [CI: 1.2–2.1], p = 0.0025.