Semaphorin 3A is another autocrine motility factor, as already described in glioblastoma [80]; it is worth noting that the initial identification of the Semaphorin 3A–Neuropilin-1 (a canonical constituent of the Semaphorin 3A receptor) signalling system as an activator of cell motility in glioblastoma resulted initially from a systematic proteomic screen performed in the HT1080 human fibrosarcoma cells [80], providing an independent confirmation of our results. The gene discussed is NRP1; the disease is glioblastoma.