ABCB1 and neoplasm: It was evidenced that patients with the “CT/TT” genotype of ABCB1 (C1236T) gene showed better tumor response to docetaxel therapy than those with “CC” in course of neoadjuvant chemotherapy for locally advanced breast cancer [17], but it was associated with higher neurotoxicity in non-small-cell lung cancer (NSCLC) treated with taxane-based regime.