BRCA1 and breast cancer: Pathway-IPA analysis on the 492 group (i) CNA facilitator genes mapped their functions as mitotic regulator genes, including the Kinetochore Metaphase Signaling Pathway (Supplementary Figure S2A), Mitotic Roles of Polo-Like Kinase, Role of CHK Proteins in Cell Cycle Checkpoint Control, Cell Cycle: G2/M DNA Damage Checkpoint Regulation, Role of BRCA1 in DNA Damage Response, Hereditary Breast Cancer Signaling, Estrogen-mediated S-phase Entry, Protein Ubiquitination Pathway, ATM Signaling, Cell Cycle Control of Chromosomal Replication, and Mismatch Repair in Eukaryotes (Supplementary Table S1).