A previously unidentified function of KLHL7 (Kelch Like Family Member 7) and KLHL11, components of the BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex, in lung adenocarcinoma genomic instability was also suggested (q = 0.0003, 0.04, respectively). Here, KLHL11 is linked to lung adenocarcinoma.