Seven other 26S/20S proteasome subunits were isolated (q < 0.05; PSMD12, PSMB4, PSMA6, PSMB6, PSMC1, PSMD3, and PSMB3), illuminating the importance of the 26/20S proteasome integrity in lung adenocarcinoma genome maintenance. This evidence concerns the gene PSMD12 and lung adenocarcinoma.