ESR1 and breast carcinoma: Bertrand and co-workers reported the conjugation of the pyrazine-based pincer gold(III) complex [Au(bbfpz)(acbim)]+(bbfpz = 2,6-bis(4-(tert-butyl)phenyl)pyrazine; acbim = 1-methyl-3-(4-(6-aminohexyl)carboxamido)benzylbenzimidazol-2-ylidene) to a derivative of 17α-ethinylestradiol (19, Figure 8), aiming to increase its selectivity towards ER(+) breast cancer cells [77].