However, to the best of our knowledge, no study has explored the effect of miRNAs that directly target anti-apoptotic molecules such as B-cell lymphoma-2 (Bcl-2), Bcl-2 lymphoma-extra large (Bcl-xL) and Myeloid cell leukemia-1 (McL-1) in chondrosarcomas. This evidence concerns the gene MCL1 and chondrosarcoma.