Ongoing proteomics studies of bronchoalveolar lavage identified new molecular factors (IFN-γ, PDGFBB, Fit3L, IL-2, TNF-β, CCL27, CXCL7, CTAP-III, GM.CSF, HPLN1, trypsin2, cathepsin G, ARSB, PSA2, etc.)that are elevated in severe asthma patients, compared to those with mild or moderate asthma. Here, PPBP is linked to asthma.