In pancreatic lysates of both KCCux1 (Figure 4C) and KCCux1p110 (Figure S4B) mice, we were able to detect increased EGFR protein levels compared to KC and control mice, with a concomitant phosphorylation of EGFR (pY1068) indicating its enhanced activation in KCCux1 mice. Here, EGFR is linked to keratoconus.