CD5 and inflammatory bowel disease: Our recent clinical association studies in patients afflicted of inflammatory bowel diseases (IBD) also anticipates association of CD5 variation with location (rs2241002CC) and requirement of biological therapies (rs2241002C-rs2229177T haplotype; Pro224-Val471) in Crohn disease, (CD) and with poor prognosis (rs2241002T-rs2229177T haplotype; Leu224-Val471) in ulcerative colitis (UC) [72].