Correia et al., through a comparison of miR-146b-5p levels between T-ALL primary cells, T-ALL cell lines, normal T-cells, thymocytes, CD34+ hematopoietic progenitor cells, and bone marrow precursors, confirmed that TAL1+ patients had lower miRNA-146b-5p levels. The gene discussed is CD34; the disease is acute lymphoblastic leukemia.