The tumor size was larger (1.006 ± 0.829 versus 2.285 ± 1.938, p = 0.035), and extrathyroidal extension, resection margin involvement and angioinvasion were significantly higher in the TERT promoter mutation group, and the T, N, and overall stage of these patients were more advanced. The gene discussed is TERT; the disease is neoplasm.