In patients with non-small-cell lung cancer, who were treated with PD-(L)1 inhibitors, baseline corticosteroid use of ≥10 mg of prednisone or equivalent was associated with poorer outcome, although it remains unclear whether baseline corticosteroids represent correlation (e.g., patients with aggressive disease) or causation [48]. The gene discussed is CD274; the disease is non-small cell lung carcinoma.