KLF1 and hemoglobinopathy: Wang et al. [40] provided further evidence that KLF1 plays a significant role in controlling HbF levels, in a study involving 140 Chinese samples with high HbF levels (>1.5%), with the cohort consisting of patients with coexisting α–thalassemia (n = 12), β–thalassemia (n = 55), and 73 samples with no evidence of hemoglobinopathies other than elevated HbF.