In adults with T2DM, the interruption of prolonged sitting with light intensity walking or simple resistance activities (e.g., half-squats, knee/calf raises, and gluteal contractions) for 3 min every 30 min over 8 h decreases postprandial glucose, insulin, C-peptide, and triglyceride levels [75]. This evidence concerns the gene INS and type 2 diabetes mellitus.