Transcript levels of CDX2, a homeobox transcription factor essential for intestinal cell growth and differentiation and a molecular trigger in IM and gastric carcinogenesis, and c-Myc, a transcription factor associated with gastric cancer progression, were assessed, and correlation with POPDC1 and POPDC3 expression was calculated [8,11,33]. The gene discussed is POPDC3; the disease is gastric cancer.