Moreover, blood levels of IL6 [158], IL8 [158,159] and interleukin 1β (IL1β) [159] as well interleukin 1 receptor antagonist (IL1ra) [159] and IL10 [159] are higher in severe NEC compared to mild or moderate NEC [159]. The gene discussed is CXCL8; the disease is necrotizing enterocolitis.