In a rat NEC model, enteral administration of Saccharomyces boulardii increased the mRNA expression of SOD-1 [135], SOD-3 [136], GSH-Px-1 [135], GSH-Px-3 [135], GSH-Px-4 [135], GHS-Px-7 [135] and CAT [135] in the terminal ileum. This evidence concerns the gene SOD1 and necrotizing enterocolitis.