In multivariate Cox regression analysis, the levels of miR-192 (HR: 3.44, 95% CI: 1.32–8.91; p = 0.01), miR-146a (HR: 0.22; 95% CI: 0.061–0.81, p = 0.02), Child Pugh Score (HR: 3.08; 95% CI: 1.65–5.72, p < 0.001), and AFP (HR: 2.1; 95% CI: 1.52–2.92, p < 0.001) were independent predictors of OS in HCC patients (Figure 5). This evidence concerns the gene AFP and hepatocellular carcinoma.