Lethal mitophagy progressed following dynamin-related protein 1 (DRP1) fission of mitochondria involving protein kinase A (PKA) inhibition and reduced phosphorylation of Fms-like tyrosine kinase 3 (FLT3) in acute myeloid leukemia cells from patients and immunocompromised mice [154] (p. 3). This evidence concerns the gene DNM1L and acute myeloid leukemia.