The 2013 WHO classification of sarcomas [28] defines tumors carrying the pathognomonic FET–ETS gene fusions, in which a member of the FET gene family is fused with an ETS transcription factor, with the most common fusion being EWSR1–FLI1, as ‘Ewing sarcoma’ [29]. The gene discussed is EWSR1; the disease is Ewing sarcoma.