Since some K15 (Keratin 15, a bona fide marker of eHFSCs) positive cells also co-express vimentin [43], this suggests that some eHFSCs in FFA HFs undergo EMT [43] and contribute to the prominent fibrosis observed in FFA, which in addition to eHFSC apoptosis observed in FFA, functions to deplete the bulge stem cell niche even further. The gene discussed is VIM; the disease is Hand-foot syndrome.