Despite the respiratory and immune systems being the crucial targets of SARS-CoV-2, prominent acute proximal tubular injury, peritubular erythrocyte aggregation, glomerular fibrin thrombi with ischemic collapse, and prominent expression of ACE2 staining on proximal tubular cells have been noted from autopsy findings on deceased COVID-19 patients [21], implying that this tough virus may also attack the kidney. The gene discussed is ACE2; the disease is COVID-19.