PZP and neoplasm: This study showed that FBN1, THBS1 and ITIH3, involved in platelet activation, signalling and aggregation, change across different tumour types and appear to be sensitive to general blood cancer biology, while Pregnancy zone protein (PZP), as previously reported in the literature, confirmed to be significantly changed in the serum of PCa patients, thus emerging as a potential specific candidate biomarker of PCa [42].