TYRP1 and neoplasm: CD14+ monocyte derived M-CSF macrophages efficiently induced ADCP of B16F10-gp75 cells, particularly through afucosylated hIgG1-TA99, which resulted in a significantly decreased number of remaining tumor cells and an increased number of tumor-cell positive macrophages, which we previously showed to reflect phagocytosis (Figure 2F and [40]).