Examples are the measurement in the bloodstream of different cancer-related biomarkers, i.e., alfa-fetoprotein (AFP), carcinoembryonic antigen (CEA), prostate specific antigen (PSA) and cancer antigen 125 (CA-125), for detection and monitoring of colorectal, prostate and ovarian malignancies, respectively [13]. The gene discussed is MUC16; the disease is cancer.