Aberrantly increased expression and TIS of E-cadherin in intralymphatic/intravascular emboli, compared with both normal epithelium and immunopositive neoplastic cells, was observed in seven tumors (7/17; 3/7 undifferentiated, 1/8 signet-ring cell and 3/5 tubular carcinoma). This evidence concerns the gene CDH1 and tubular adenocarcinoma.