IL-17A plays a key pathogenic role in asthma, as it induces some of the growth-related oncogene (GRO) chemokine production (e.g., CXCL2 and CXCL3) [82], which enhance asthmatic airway smooth muscle cell (ASMC) migration by inducing ERK1/2 and p38 MAPK signaling pathways activation via CXCR1 and CXCR2 chemokine receptors [83]. The gene discussed is IL17A; the disease is asthma.