Contrary to what was previously reported in several NB cell lines [30], NB-MSCs cells displayed high levels of MHC-I and multifactorial resistance to NK cell-mediated lysis, including natural cytotoxicity and resistance to antibody-dependent cell-mediated cytotoxicity (ADCC) using both anti-CD105 IgG TRC105 and anti-GD2 mAb dinutuximab [50]. Here, ENG is linked to neuroblastoma.