EHMT2 and hepatocellular carcinoma: Since functional evaluations of G9a in HCC from previous studies were mostly performed using problematic cell lines, we first selected four HBV-positive (HBV+) (HCC36, Hep3B, PLC/PRF/5, and Huh1) and three HBV-negative (HBV−) (Mahlavu, Huh6, and Huh7) HCC cell lines [33,34] which were not reported to be problematic cell lines and evaluated their G9a expression levels.