As a mere example, the HML7 locus 2q11.2 was found to be upregulated in human PBMC following innate immunity stimulation by a mimicked bacterial infection [45], while no modulation was observed in the presence of viral infections (HIV [46] and SARS-CoV-2, Grandi et al., unpublished data) or autoimmunity (multiple sclerosis—Grandi et al., unpublished data). This evidence concerns the gene SLC25A16 and bacterial infectious disease.