Given that compound 5824 was suggested to bind to the NAAD binding site in the NAD synthetase of B. subtilis [133,134], which was found to share a very high degree of residue conservation with the NAAD binding site of the human NAD synthetase 1 (NADSYN1), Chowdhry and colleagues employed compound 5824 as a human NADSYN1 inhibitor in cancer models [37]. Here, NADSYN1 is linked to cancer.