FASN and melanoma: Spearman’s correlation between gene expression data of FASN and the IC50 values of PLX4720 (a structurally distinct analog of PLX4032) across BRAF-mutated melanomas indicated that FASN levels were inversely correlated with IC50 values both at gene (rs = −0.5) and protein level (rs = −0.53) (Figure 1C).