Others reported that, in 48 patients, at least one type of mutation among TP53 (c.747G > T), CTNNB1 (c.121A > G, c.133T > C), or TERT (c.1-124C > T) was documented in 56.3% of patients; only 22.2% of patients had matched mutations in HCC tissue, while none of these mutations were found in non-tumoral liver tissue or in peripheral mononuclear cells [54]. This evidence concerns the gene CTNNB1 and hepatocellular carcinoma.