AFP and hepatocellular carcinoma: Total amount of cfDNA: HCC vs. healthy subjects: 52%/95%; 0.80Allelic imbalance at D8S258 in the plasma of 62% of patientsAllelic imbalance at D8S264 in the plasma of 60% of patientsHigh cfDNA concentration + allelic imbalance abnormal in 8/24 patients with low AFP