Sipuleucel-T is an autologous DC vaccine based on enriched blood APCs cultured with a recombinant protein derived from the combination of prostatic acid phosphatase (PAP) with granulocyte-macrophage colony-stimulating factor (GM-CSF), that are, respectively, an antigen expressed in prostate cancer tissue and an immune cell activator [86]. Here, CSF2 is linked to Familial prostate cancer.