BRCA1 and neoplasm: Multivariate Cox model analysis (Table 5) confirmed that the patients with two worse prognosis factors exhibited an increased risk of death, such as the patients with double decreased ATM and BRCA1 mRNAs (HR = 4.195, 95% CI: 1.779–9.892), downregulated ATM and large tumor (HR = 5.519, 95% CI: 2.456–12.405) or positive lymph node (HR = 5.143, 95% CI: 2.202–12.015), and downregulated BRCA1 and large tumor (HR = 6.517, 95% CI: 2.204–19.264) or positive lymph node (HR = 5.543, 95% CI: 2.005–15.326).