In line with our meta-analysis, NRG1 protein was shown to express in 100% (3 of 3) of normal prostate tissues with moderate cytoplasmic/membranous expression, whereas the expression was undetectable in all (0 of 12) prostate cancer tissues from The Human Protein Atlas, confirming that NRG1 protein expression is downregulated in prostate cancer. Here, NRG1 is linked to Familial prostate cancer.