Based on data analysis of glioma TCGA (n = 667) and CGGA datasets (n = 633), the mRNA levels of FAP were significantly elevated in GBM compared to healthy brain tissues and lower grade glioma tissues, and a higher level of FAP was related to poorer prognosis across gliomas of all grades (TCGA dataset analysis HR = 0.36; CGGA dataset analysis HR = 0.51) [10]. The gene discussed is FAP; the disease is central nervous system cancer.