Although there is still limited evidence of CAFs or CAF-like cells in GBM [21], Li et al. recently identified increased FAP+/PDGFRβ+ cell populations in clinical glioma specimens as well as murine GBM models, suggesting that these cells are the major tumor-associated pericyte-like stromal cells within the GBM microenvironment [10]. The gene discussed is FAP; the disease is glioma.