For example, Zhang et al. used chlorin 6-mediated PDT combined with either an inhibitor for PD1/PDL1 interaction called Bristol Mayers Squibb 202 (BMS-202), or an anti-PDL1 antibody treated 4T1 murine breast cancer model and showed that tumor regression was associated with the inhibition of lung metastasis. The gene discussed is PDCD1; the disease is breast carcinoma.