Although the etiopathology of ASD remains unknown, there is a consensus regarding the relevance of its heritable/genetic basis, confirmed in various human twin studies [6] and animal models that show a simplified ASD-like phenotype, as in the case of the fragile X mental retardation (FMR1)-KO rodents, the BTBR models, and the neuroligin 3 (Nlgn3)-KO rodents, amongst others [7]. This evidence concerns the gene NLGN3 and Intellectual disability.