To date, several risk factors for stroke in patients with ESRD on dialysis have been reported, and include diabetes mellitus (DM), hypertension, atrial fibrillation (Af), old age, anemia, malnutrition, asymmetric dimethylarginine, and elevated C-reactive protein (CRP) [4,6,10,11,12,13,14]. The gene discussed is CRP; the disease is atrial fibrillation.