An analysis of plasma has revealed many upregulated lncRNAs as biomarkers in different cancers, such as HOTAIR (breast cancer) [76], LNCV6 family (colorectal cancer) [77], SOX2-OT (lung squamous cell carcinoma) [78], as well as SAP30L-AS1 and SChLAP1 (prostate cancer) [79]. This evidence concerns the gene SOX2 and cancer.