Based on the 39 core common genes, immune system, cytokine/inflammatory response, signaling by interleukins, TNF-α signaling via NF-kB, IL-6/JAK/STAT3 signaling, TLR signaling, and AGE-RAGE signaling pathways, etc., are found as links between CVD and COVID-19 (Supplementary Table S5). This evidence concerns the gene STAT3 and COVID-19.