As dyslipidemia is often present in patients with myocardial infarction and is known to have detrimental effects on remodeling and postinfarction cardiac function [16,17], using ApoE−/− mice, we investigated the effect of miR155 deficiency on cardiac function and remodeling following myocardial infarction in the context of dyslipidemia. The gene discussed is APOE; the disease is metabolic syndrome.