TSPAN8 and colorectal carcinoma: In fact, seven mRNAs (annexin A3, C-type lectin domain family 4 (member D), lamin B1, proline rich gla, tumor necrosis factor, vanin 1 and interleukin 2 receptor beta) and three mRNAs (TSPAN8, lectin galactoside-binding soluble 4 and collagen type I alpha 2 chain) in blood were used by Rodia et al. (2016) and Marshall et al. (2010) [49,59], respectively, to detect CRC patients.